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NEET MCQs Inheritance and Variation

NEET MCQs Inheritance and Variation – Sample

  1. A haemophilic woman marries a normal man, then
    a) All the children will be normal b) All the sons will be haemophilic
    c) All the girls will be haemophilic d) Half girls will be haemophilic
  2. Disorder inherited as Mendel’s law of inheritance called
    a) Mendelian disorder b) Chromosomal disorder
    c) Maternal inheritance d) Polygenic inheritance
  3. The term ‘gene’ was coined by
    a) Avery b) Bateson c) Johanssen d) Mendel
  4. The phenotypic ratio in the 𝐹2 gereration of dihybrid cross, is
    a) 9 : 3 : 3 : 1 b) 1 : 2 : 2 : 4 : 1 : 2 : 1 : 2 : 1
    c) 7 : 1 : 1 : 7 d) 12 : 8 : 4
  5. Chromosome is made up of
    a) DNA +pectin b) RNA +DNA c) DNA +histone d) Only histone
  6. Select the incorrect statemant from the following.
    a) Linkage is an exception to the principle of
    independent assortment in heredity
    b) Galactosemia is an inborn error of metabolism
    c) Small population size result in random genetic
    drift in a population
    d) Baldness is a sex-limited trait
  7. A pure tall and a pure dwarf plant were crossed to produced offsprings. Offsprings were self crossed, then
    find out the ratio between true breeding tall to true breeding dwarf?
    a) 1 : 1 b) 3 : 1 c) 2 : 1 d) 1 : 2 : 1
  8. Exposure of X-rays enhances the frequency of
    a) Linkage b) Crossing over
    c) Pairing of chromosome d) Segregation
  9. A self-fertilizing trihybrid plant forms
    a) 8 different gametes and 64 different zygotes b) 4 different gametes and 16 different zygotes
    c) 8 different gametes and 16 different zygotes d) 8 different gametes and 32 different zygotes
  10. Genotype is the
    a) Genetic constitution b) Genetic constitution of the phenotype
    c) Trait expressed d) Expressed genes
  11. Failure of cytokinesis after …A… stage of cell division results in an increase in a whole set of chromosomes
    in an organism called …B…
    a) A-prophase, B-polyploidy b) A-metaphase, B-polyploidy
    c) A-anaphase, B-polyploidy d) A-telophase, B-polyploidy
  12. In previous question find out total seeds (plants) having round seed texture
    a) 12 b) 10 c) 9 d) 11
  13. The ratio 1 : 1 : 1 : 1 is obtained from a cross between the parents
    a) RRYY×rryy b) RRYY×rryy c) RRYY×Rryy d) RrYy×rryy
  14. Which of the following terms represent a pair of contrasting characters?
    a) Homozygous b) Heterozygous c) Allelomorphs d) Codominant genes

NEET MCQs Inheritance and Variation – Page| 2

  1. Harmful mutation does not get eliminated from the gene pool because they are mainly
    a) Dominant, which have beneficial effect on population and carried by heterozygous individuals
    b) Dominant, which have beneficial effect on population and carried by homozygous individuals
    c) Carried from one generation to another generation through autosomal chromosomes
    d) They show genetic drift
  2. Incomplete linkage is …A… . Complete linkage is …B… . Choose correct option for A and B
    a) A-common, B-rare b) A-rare, B-common
    c) A-impracticle, B-practicle d) A-practicle, B-impracticle
  3. Mendelism was rediscovered by
    I. Morgan
    II. De Vries
    III. Correns
    IV. Tschermark
    Choose the correct option
    a) I, III and IV b) I, II, III and IV c) II, III and IV d) I, II and III
  4. In gynandromorphs,
    a) Some cells of body contain XX and some cells with genotype XY
    b) All cells have XX genotype
    c) All cells have XY genotype
    d) All cells with genotype XXY
  5. Example of interagenic gene interaction is/are
    a) Incomplete dominance b) Codominant
    c) Multiple alleles d) All of the above
  6. If a cross between two individuals produces offspringe with 50% dominant character (A) and 50%
    recessive character (a),then the genotypes of parents are
    a) Sex linked genes b) Pseudoallelic genes
    c) Intermediate inheritance d) Dominant and recessive genes
  7. Which is correct about traits choosen by Mendel for his experiment on pea plant?
    a) Terminal pod was dominant b) Constricted pod was dominant
    c) Green coloured pod was dominant d) Tall plants were recessive
  8. Codominance is found in
    a) Plants b) Animal c) Both (a) and (b) d) Prokaryote
  9. During Mendel’s investigation, it was first time that …A… and …B… were applied in biology. Here A and B
    refers to
    a) A-statistical analysis; B-mathematical logic
    b) A-statistical analysis; B-physical logic
    c) A-statistical analysis; B-chemistry logic
    d) A-statistical analysis; B-simple logic
  10. The chromosomal denotation for heterogametic female and homogametic male are
    a) ZW and ZZ b) ZO-ZZ c) XX-XO d) Both (a) and (b)
  11. Pure tall plants are crossed with pure dwarf plants. In the F1-generation, all plants were tall. These tall
    plants of F1-generation were selfed and the ratio of tall to dwarf plants obtained was 3: 1. This is called
    a) Dominance b) Inheritance c) Codominance d) heredity
  12. The best method to determine the homozygosity and heterozygosity of an individual is
    a) Self-fertilisation b) Back cross c) Test cross d) Inbreeding
  13. A medical technician, while observing a human blood smear under the microscope notes the presence of a
    Barr body close to the nuclear membrane in the WBC. This indicates that the person under investigation is
    a
    a) Colourblind b) Haemophilic c) Normal female d) Normal male
  14. Find out 𝐴,𝐵 and 𝐶 in the diagram given below in

NEET MCQs: Inheritance & Variation – Page| 3

a) A-Male, B-Female, C-Gametes b) A-Male, B-Female, C-Sperm
c) A-Female, B-Male, C-Gametes d) A-Gametes, B-Male, C-Female

  1. In Turner’s syndrome
    a) Female is fertile b) Male is fertile c) Female is sterile d) Male is sterile
  2. The most likely reason for the development of resistance against pesticides in insect damaging a crop is
    a) Random mutations b) Genetic recombination
    c) Directed mutations d) Acquired heritable changes
  3. Lampbrush chromosomes sre seen in
    a) Interphase b) Zygotene c) Diplotene d) metaphase
  4. In case of incomplete dominance, what will be the phenotypic ratio of 𝐹2generation?
    a) Histones b) Hydrocarbons c) Polynucleotides d) Lipoproteins
  5. Examples of dissimilar sex chromosomes are given below
    I. XX – XY ⇒ I
    II. XX – XO ⇒ II
    I and II in the above statement can be
    I II a) Man and most
    insect
    Cockroach and
    roundworms

b) Cockroach and
roundworms
Man and most
insect

c) Butterfly Fishes

d) Bird Reptiles

  1. Mutations, which alter nucleotide sequence within a gene are
    a) Frameshift mutation b) Base pair substitutions
    c) Both (a) and (b) d) None of these
  2. The 𝐹1generation has all tall, and 𝐹2ratio is 3 : 1, it proves
    a) Law of dominance b) Independent assortment
    c) Law of segregation d) linkage
  3. Mendel’s law were true for situation in which
    a) Alleles are affected by their environment b) Alleles shows complete dominance
    c) Alleles of a gene alter the affect of a different gene d) A given character is determined by more than one
    gene
  4. Blood group-O has
    a) No antibodies b) No antigens c) a or b antibodies d) A and B antigens
  5. Wilson detected the colour blindness disease in
    a) 1921 b) 1911 c) 1912 d) 1910
  6. In a dihybrid cross between RRYY and rryy parents, the number of RrYy genotypes in 𝐹2generation will be
    a) 4 b) 3 c) 2 d) 1
  7. If a cross between two individuals produces offspringe with 50% dominant character (A) and 50%
    recessive character (a),then the genotypes of parents are
    a) Genic interactions controlling a character b) Multiple genes controlling a character
    c) Expression of many characters by a single gene d) Alternative forms of a gene at a given locus
  8. A women with albinic father marries an albinic man.the proportion of her progeny is
    a) 2 normal : 1 albinic b) All normal
    c) All albinic d) 1 normal : 1 albinic
NEET MCQs: Inheritance & Variation – Page| 4
  1. When one sex chromosome is lacking in female and males are homogametic, in that condition, the sex
    chromosomal representation is
    a) ZO-ZZ b) XY-XX c) XX-XO d) ZW-ZZ
  2. Some individuals with blood group –A may inherit the genes for blonde hair, while other individuals with
    blood group – A may the gene for brown hair. This can be best explained by the principle of
    a) Dominance b) Multiple alleles
    c) Independent assortment d) Incomplete dominance
  3. In bugs and cockroaches, the sex determination takes place by
    a) XX and XO chromosomes b) XX and XY chromosomes
    c) ZZ-ZW chromosomes d) ZO-ZZ chromosomes
  4. The two …A… separate and pass into two daughter nuclei and cells during mitosis. Similarly, each …B…
    replicates, with one pair passing into each daughter cell during mitosis. This maintains the similar …C… of
    all the cells.
    Find out correct option for A, B and C
    a) A-chromatid, B-allele pair, C-morphology b) A-chromatid, B-allele pair, C-genetic composition
    c) A-organ, B-organ pair, C-individuality d) A-unlinked gene, B-linked gene, C-morphology
  5. The shape of chromosome is determined by
    a) Centrosome b) Centromere c) Chromomere d) telomere
  6. Mendel was a
    a) Austrian biology teacher b) Austrian monk
    c) Austrian scientist d) Austrian mathematician
  7. Who clearly proved and define linkage?
    a) Morgan b) Castle c) Bateson d) Punnett
  8. Improvement of human race through hereditary qualities is called
    a) Euthenics b) Human heredity c) Human demography d) Eugenics
  9. Test cross involves
    a) Crossing between two genotypes with recessive trait
    b) Crossing between two F1-hybrids
    c) Crossing the F1-hybrid with a double recessive genotype
    d) Crossing between two genotypes with dominant trait
  10. When a diploid female plant is crossed with a tetraploid male, the ploidy of endosperm cells in the
    resulting seed is
    a) Tetraploidy b) Pentaploidy c) Diploidy d) Triploidy
  11. Colour blindness is
    a) Sex-linked recessive disease
    b) Sex-linked dominant disease
    c) Autosomal dominant disease
    d) Autosomal recessive disease
  12. A condition, where a certain gene is present in only a single copy in a diploid cell, is called
    a) Four different types of gametes produed by the 𝐹1
    dihybrid b) Homozygous condition of the 𝐹1-dihybrid
    c) Four different types of 𝐹1-dihybrids d) Four different types of gametes produed by the

    �1-parent
  13. If the blood group of a child is A and of mother is B, then the genotype of mother and father may be
    a) BB×AA b) AB×AB c) BO×OO d) BO×AO

  14. symbol in pedigree analysis represents
    a) Still birth b) Still death c) Still carrier d) Still mating
  15. Which amino acids are present in histones?
    a) Lysine and histidine b) Valine and histidine
NEET MCQs: Inheritance & Variation – Page| 5

c) Arginine and lysine d) Arginine and histidine

  1. Monosomic trisomy are represented as
    a) 2𝑛−1+1 b) 2𝑛−1−1 c) 2𝑛−1 d) 2𝑛+1+1
  2. Which is a sex-influenced disease?
    a) Baldness in male b) Haemophilia
    c) Xeroderma pigmentosa d) Down’s syndrome
  3. Thalassaemia is
    a) Autosomal recessive disease b) Autosomal dominant disease
    c) Sex-linked dominant disease d) Sex-linked recessive disease
  4. Mutation is phenomena which results in alternation of
    a) Sequence b) Carbohydrates c) Proteins d) Fat
  5. A man with normal vision whose father was colourblind marries with women whose father was also
    colourblind. Suppose their first child is daughter then what are the chances of this child to be colourblind?
    a) 100% b) 25% c) 50% d) 0%
  6. Gamete mother cells of the chromosome 44 + XY suffers from non-disjunction at first meiotic division.
    Which of the following set of gametes would result?
    a) 22 + XX, 22 + XY, and 22, 22 b) 22 + XY, 22 + XY, and 22, 22
    c) 22 + X, 22 + Y, and 22 + Y, 22 d) 22 + X, 22 + XY, and 22 + Y, 22 + Y
  7. Law of Mendel, which is not completely applicable is?
    a) Codominance b) Law of segregation
    c) Law of independent assortment d) Law of dominance
  8. Low pitched voice, beared and moustaches, belong to the
    a) Sex limited traits b) Sex linked trait c) Nullisomic traits d) Sex influenced traits
  9. Multiple allele can be manifested only when there is the study of
    a) Individual organism b) Genus c) Population d) Phylum
  10. 𝑁𝑖𝑐𝑜𝑡𝑖𝑎𝑛𝑎 𝑠𝑦𝑙𝑣𝑒𝑠𝑡𝑟𝑖𝑠 flowers only during long days and 𝑁.𝑡𝑎𝑏𝑎𝑐𝑢𝑚 flowers only during short days, if
    raised in the laboratory under different photoperiods, they can be induced to flower at the same time and
    can be cross fertilized to produce self-fertile offspring. What is the best reason for considering N. sylvestris
    and N. tobaccum to be separate species?
    a) They are physiologically distinct b) They are morphologically distinct
    c) They cannot interbreed in nature d) They are reproductively distinct
  11. The following diagram shows two types of chromosomal mutations

Give the name or type of mutation in respect to A and B
a) A-Duplication, B-Substitution b) A-Duplication, B-Deletion
c) A-Inversion, B-Deletion d) A-Inversion, B-Substitution

  1. How many different kinds of gametes will be produced by a plant having the genotype AABbCC?
    a) Three b) Four c) Nine d) Two
  2. Down’s syndrome and Turner’s syndrome occur in human beings due to
    a) Monosomic and nullisomic conditions respectively b) Monosomic and trisomic conditions respectively
    c) Trisomic and monosomic conditions respectively d) Trisomic and tetrasomic conditions respectively
  3. What are all the chances of colourblind daughters of a normal man marrying normal women whose father
    was colourblind?
    a) All sons are normal and all daughters are
    colourblind
    b) Both the sons and daughters are phenotypically
    normal

NEET MCQs: Inheritance & Variation – Page| 6

c) All the sons are colourblind and all daughters are
normal
d) 50% sons are colourblind and all daughters are
phenotypically normal

  1. In males, pattern baldness is related to both autosomal genes as well as excessive secretion of
    a) Oestrogen b) Growth hormone c) Testosterone d) Inhibits
  2. Which of these is not a Mendelian disorder?
    a) Cystic fibrosis b) Sickle-cell anaemia c) Colourblindness d) Turner’s syndrome
  3. Which of the following is not true of haemophilia?
    a) Royal disease b) Bleeder’s disease
    c) X-linked disorder d) Y-linked disorder
  4. If heterozygous dominant (tT) crossed with homozygous dwarf plant, then the percentage of progeny
    having dwarf character is
    a) 60% b) 40% c) 50% d) 70%
  5. Mutations are generally induced by means of
    a) 𝛼−𝑟𝑎𝑦𝑠 b) β−𝑟𝑎𝑦𝑠 c) 𝛾−𝑟𝑎𝑦𝑠 d) UV radiations
  6. Two crosses between the same pair of genotypes or phenotypes, in which the sources of the gametes are
    reversed in one cross, is known as
    a) Dihybrid cross b) Reverse cross c) Test cross d) Reciprocal cross
  7. A hereditary, disease, which is never passed on from father to son is
    a) X-chromosomal linked disease b) Autosomal linked disease
    c) Y-chromosomal linked disease d) None of the above
  8. Bateson used the term coupling and repulsion for linkage and crossing over. Choice the correct coupling
    and repulsion combination
    Coupling Repulsion a) AABB, aabb AAbb, aaBB

b) AABB, aabb AABB, AAbb

c) AAbb, aaBB AaBb, aabb

d) aaBB, aabb AABB, aabb

  1. In blood group typing in human, if an allele contributed by one parent is IAand an allele contributed by the
    other parent is i, the resulting blood group of the offspring will be
    a) A b) B c) AB d) O
  2. A person having 45 chromosomes and Y-chromosome absent. Is suffering from
    a) Down’s syndrome b) Klinefelter’s syndrome
    c) Turner’s syndrome d) gynandromorph
  3. Linkage and crossing over are
    a) Same phenomena b) Different phenomena
    c) Opposite phenomena d) Identical phenomena
  4. The modern concept of gene is
    a) A segment of DNA, capable of crossing over b) Functional unit of DNA
    c) A segment of RNA d) A segment of chromosome
  5. Females in haplodiploidy sex determination are
    a) N b) 2n c) 1
    2
    n d) 3n
  6. Using imprints from a plate with complete medium and carrying bacterial colonies, you can select
    streptomycin resistant mutants and prove that such mutations do not originate as adaptation. These
    imprints need to be used
    a) Only on plates with streptomycin b) On plates with minimal medium
    c) Only on plates without streptomycin d) On plates with and without streptomycin
  7. Phenylketonuria, Huntington’s disease and sickle cell anaemia are caused respectively due to disorders
    associated with
    a) Chromosome-7, chromosome-11 and chromosome-12
    b) Chromosome-11, Chromosome-4 chromosome-12
    c) Chromosome-7, chromosome-12 and chromosome-11
    d) Chromosome-12, chromosome-4 and chromosome-11

Page| 7

  1. The arrangement of genes on chromosome is
    a) Linear b) Oviod c) Diffused d) Spiral
  2. When two genetic loci produce identical phenotypes in 𝑐𝑖𝑠 and 𝑡𝑟𝑎𝑛𝑠 position, they are considered to be
    a) Pseudoalleles b) Multiple alleles
    c) The part of same gene d) Different genes
  3. Which of the following matches correctly?
    a) Factor –II – Thromboplastin b) Factor –III – Prothrombin
    c) Factor –VIII – Antihaemophilic globulin d) Factor –XII – Haemophilic
  4. The longest chromosomes is seen in
    a) Allium b) Lilium c) Trillium d) Zea mays
  5. Mendel observed that ….. generation shows always phenotype of dominant parent
    a) F4 b) F2 c) F1 d) F0
  6. …A… genes are those which occurs on the same chromosome and …B… genes are those, which are present
    on different chromosome.
    Choose correct choice for A and B
    a) A-linked; B-unlinked gene b) A-unlinked; B-linked
    c) A-identical; B-non-identical d) A-non-identical; B-identical
  7. Allelic sequence variations where more than one variant (allele) at a locus in a human population with a
    frequency greater than 0.01 is refered to as
    a) Incomplete dominance b) Multiple allelism
    c) SNP d) DNA polymorphism
  8. The possibility of a female becoming a haemophilia is …A… rare because mother of such a female has to be
    at least …B… and the father should be …C…
    Choose the correct option for A, B and C
    a) A-extremely, B-carrier, C-haemophilic
    b) A-extremely, B-carrier, C-carrier
    c) A-extremely, B-haemophilic, C-carrier
    d) A-extremely, B-haemophilic, C-haemophilic
  9. If the foetus is Rh+ and mother is Rh−, then
    a) Foetus will transmit antigen to mother blood
    b) Foetus will transmit antibody to mother blood
    c) Foetus is attacked by antibodies to mother blood
    d) Foetus is attacked by antigen to mother blood
  10. The most popularly known blood grouping is the ABO grouping. It is named ABO and not ABC, because ‘O’
    in it refers to having
    a) Other antigens besides A and B on RBCs b) Over dominance of this type on the genes for A
    and B types
    c) One antibody only−either anti-a or anti–b on the
    RBCs
    d) No antigens A and B on RBCs
  11. Alleles are
    a) Alternate forms of a gene b) Homologous chromosome
    c) Pair of sex chromosome d) None of the above
  12. Telomere repetitive DNA sequences control the function of eukaryotic chromosomes because they
    a) Act as replicons b) Are RNA transcription initiator
    c) Help chromosome pairing d) Prevent chromosome loss
  13. Genotypic and phenotypic ratios remains the same in
    a) Sex-linked genes b) Pseudoallelic genes
    c) Intermediate inheritance d) Dominance and recessive genes
  14. Mendelian disorder may be of
    a) Recessive b) Dominant c) Both (a) and (b) d) Can’t be determined

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